Anti-TCR Antibody Treatment Activates a Novel Population of Nonintestinal CD8 TCR Regulatory T Cells and Prevents Experimental Autoimmune Encephalomyelitis
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چکیده
منابع مشابه
Antigenized antibodies expressing Vβ8.2 TCR peptides immunize against rat experimental allergic encephalomyelitis
BACKGROUND: Immunity against the T cell receptor (TCR) is considered to play a central role in the regulation of experimental allergic encephalomyelitis (EAE), a model system of autoimmune disease characterized by a restricted usage of TCR genes. Methods of specific vaccination against the TCR of pathogenetic T cells have included attenuated T cells and synthetic peptides from the sequence of t...
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